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Hippo pathway genes developed varied exon numbers and coevolved functional domains in metazoans for species specific growth control

BACKGROUND: The Hippo pathway controls growth by mediating cell proliferation and apoptosis. Dysregulation of Hippo signaling causes abnormal proliferation in both healthy and cancerous cells. The Hippo pathway receives inputs from multiple developmental pathways and interacts with many tissue-speci...

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Detalles Bibliográficos
Autores principales: Zhu, Henan, Zhou, Ziwei, Wang, Daxi, Liu, Wenyin, Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620549/
https://www.ncbi.nlm.nih.gov/pubmed/23547742
http://dx.doi.org/10.1186/1471-2148-13-76