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Hippo pathway genes developed varied exon numbers and coevolved functional domains in metazoans for species specific growth control
BACKGROUND: The Hippo pathway controls growth by mediating cell proliferation and apoptosis. Dysregulation of Hippo signaling causes abnormal proliferation in both healthy and cancerous cells. The Hippo pathway receives inputs from multiple developmental pathways and interacts with many tissue-speci...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620549/ https://www.ncbi.nlm.nih.gov/pubmed/23547742 http://dx.doi.org/10.1186/1471-2148-13-76 |