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Genome-wide analysis of human hotspot intersected genes highlights the roles of meiotic recombination in evolution and disease
BACKGROUND: Meiotic recombination events are not randomly located, but rather cluster at hotspot regions. Recently, the fine-scale mapping of genome-wide human recombination hotspots was performed. Here, we systematically analyzed the evolutionary and disease-associated features of hotspots that ove...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620679/ https://www.ncbi.nlm.nih.gov/pubmed/23368819 http://dx.doi.org/10.1186/1471-2164-14-67 |