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Genome-wide analysis of human hotspot intersected genes highlights the roles of meiotic recombination in evolution and disease

BACKGROUND: Meiotic recombination events are not randomly located, but rather cluster at hotspot regions. Recently, the fine-scale mapping of genome-wide human recombination hotspots was performed. Here, we systematically analyzed the evolutionary and disease-associated features of hotspots that ove...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Hu, Zhibin, Zhou, Zuomin, Guo, Xuejiang, Sha, Jiahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620679/
https://www.ncbi.nlm.nih.gov/pubmed/23368819
http://dx.doi.org/10.1186/1471-2164-14-67