Cargando…

Genome-wide analysis of human hotspot intersected genes highlights the roles of meiotic recombination in evolution and disease

BACKGROUND: Meiotic recombination events are not randomly located, but rather cluster at hotspot regions. Recently, the fine-scale mapping of genome-wide human recombination hotspots was performed. Here, we systematically analyzed the evolutionary and disease-associated features of hotspots that ove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Tao, Hu, Zhibin, Zhou, Zuomin, Guo, Xuejiang, Sha, Jiahao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620679/ https://www.ncbi.nlm.nih.gov/pubmed/23368819 http://dx.doi.org/10.1186/1471-2164-14-67

Ejemplares similares

Rapid evolution of mammalian X-linked testis microRNAs
por: Guo, Xuejiang, et al.
Publicado: (2009)

Hotspots for Initiation of Meiotic Recombination
por: Tock, Andrew J., et al.
Publicado: (2018)

An update of the macaque testis proteome
por: Zhou, Tao, et al.
Publicado: (2015)

The Role of RING Box Protein 1 in Mouse Oocyte Meiotic Maturation
por: Zhou, Lin, et al.
Publicado: (2013)

Evolution of Mutational Robustness in the Yeast Genome: A Link to Essential Genes and Meiotic Recombination Hotspots
por: Keller, Philipp J., et al.
Publicado: (2009)

Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome
por: Zheng, Jie, et al.
Publicado: (2010)

Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
por: Protacio, Reine U., et al.
Publicado: (2022)

High frequency of microsatellites in S. cerevisiae meiotic recombination hotspots
por: Bagshaw, Andrew TM, et al.
Publicado: (2008)

A susceptibility locus rs7099208 is associated with non-obstructive azoospermia via reduction in the expression of FAM160B1
por: Zhang, Yan, et al.
Publicado: (2015)

CHES-1-like, the ortholog of a non-obstructive azoospermia-associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis
por: Yu, Jun, et al.
Publicado: (2016)

Genome-Wide Control of the Distribution of Meiotic Recombination
por: Grey, Corinne, et al.
Publicado: (2009)

ARG-walker: inference of individual specific strengths of meiotic recombination hotspots by population genomics analysis
por: Chen, Hao, et al.
Publicado: (2015)

Trans-Regulation of Mouse Meiotic Recombination Hotspots by Rcr1
por: Parvanov, Emil D, et al.
Publicado: (2009)

PRDM9 points the zinc finger at meiotic recombination hotspots
por: Neale, Matthew J
Publicado: (2010)

Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
por: Storey, Aaron J., et al.
Publicado: (2018)

Genome-Wide Association Study of Meiotic Recombination Phenotypes
por: Begum, Ferdouse, et al.
Publicado: (2016)

LDSplitDB: a database for studies of meiotic recombination hotspots in MHC using human genomic data
por: Guo, Jing, et al.
Publicado: (2018)

The expression and localization of a novel protein phosphatase inhibitor 2810408A11Rik in mouse testis and sperm
por: Bi, Ye, et al.
Publicado: (2012)

Proteomic-based identification of maternal proteins in mature mouse oocytes
por: Zhang, Ping, et al.
Publicado: (2009)

Contrasted Patterns of Crossover and Non-crossover at Arabidopsis thaliana Meiotic Recombination Hotspots
por: Drouaud, Jan, et al.
Publicado: (2013)

Support vector machine for classification of meiotic recombination hotspots and coldspots in Saccharomyces cerevisiae based on codon composition
por: Zhou, Tong, et al.
Publicado: (2006)

Genome-wide survey of post-meiotic segregation during yeast recombination
por: Mancera, Eugenio, et al.
Publicado: (2011)

Genome-wide variability in recombination activity is associated with meiotic chromatin organization
por: Jin, Xiaofan, et al.
Publicado: (2021)

Meiotic Recombination Hotspots of Fission Yeast Are Directed to Loci that Express Non-Coding RNA
por: Wahls, Wayne P., et al.
Publicado: (2008)

Cis- and Trans-Acting Elements Regulate the Mouse Psmb9 Meiotic Recombination Hotspot
por: Baudat, Frédéric, et al.
Publicado: (2007)

LDsplit: screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphisms
por: Yang, Peng, et al.
Publicado: (2014)

Evolution of meiotic recombination genes in maize and teosinte
por: Sidhu, Gaganpreet K., et al.
Publicado: (2017)

Dual functions for the ssDNA-binding protein RPA in meiotic recombination
por: Shi, Baolu, et al.
Publicado: (2019)

Genome wide analysis of meiotic recombination in yeast: For a few SNPs more
por: Chakraborty, Parijat, et al.
Publicado: (2018)

Yeast model identifies ENTPD6 as a potential non-obstructive azoospermia pathogenic gene
por: Wang, Qian, et al.
Publicado: (2015)

The consequences of sequence erosion in the evolution of recombination hotspots
por: Tiemann-Boege, Irene, et al.
Publicado: (2017)

Genome-wide analysis of Fusarium graminearum field populations reveals hotspots of recombination
por: Talas, Firas, et al.
Publicado: (2015)

Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast
por: Wu, Min, et al.
Publicado: (2014)

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
por: Wells, Daniel, et al.
Publicado: (2020)

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26
por: Hirota, Kouji
Publicado: (2022)

Variation in Genome-Wide Levels of Meiotic Recombination Is Established at the Onset of Prophase in Mammalian Males
por: Baier, Brian, et al.
Publicado: (2014)

Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
por: Sun, Hequan, et al.
Publicado: (2019)

Budding Yeast Pch2, a Widely Conserved Meiotic Protein, Is Involved in the Initiation of Meiotic Recombination
por: Farmer, Sarah, et al.
Publicado: (2012)

The Case of the Fickle Fingers: How the PRDM9 Zinc Finger Protein Specifies Meiotic Recombination Hotspots in Humans
por: Ségurel, Laure, et al.
Publicado: (2011)

Prdm9, a Major Determinant of Meiotic Recombination Hotspots, Is Not Functional in Dogs and Their Wild Relatives, Wolves and Coyotes
por: Muñoz-Fuentes, Violeta, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_qhenrh6dcje4gdhb7e85npl84k