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Increased carbonylation, protein aggregation and apoptosis in the spinal cord of mice with experimental autoimmune encephalomyelitis

Previous work from our laboratory implicated protein carbonylation in the pathophysiology of both MS (multiple sclerosis) and its animal model EAE (experimental autoimmune encephalomyelitis). Subsequent in vitro studies revealed that the accumulation of protein carbonyls, triggered by glutathione de...

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Detalles Bibliográficos
Autores principales: Dasgupta, Anushka, Zheng, Jianzheng, Perrone-Bizzozero, Nora I., Bizzozero, Oscar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620690/
https://www.ncbi.nlm.nih.gov/pubmed/23489322
http://dx.doi.org/10.1042/AN20120088