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Increased carbonylation, protein aggregation and apoptosis in the spinal cord of mice with experimental autoimmune encephalomyelitis
Previous work from our laboratory implicated protein carbonylation in the pathophysiology of both MS (multiple sclerosis) and its animal model EAE (experimental autoimmune encephalomyelitis). Subsequent in vitro studies revealed that the accumulation of protein carbonyls, triggered by glutathione de...
Autores principales: | Dasgupta, Anushka, Zheng, Jianzheng, Perrone-Bizzozero, Nora I., Bizzozero, Oscar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620690/ https://www.ncbi.nlm.nih.gov/pubmed/23489322 http://dx.doi.org/10.1042/AN20120088 |
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