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Intra-membrane Signaling Between the Voltage-Gated Ca(2+)-Channel and Cysteine Residues of Syntaxin 1A Coordinates Synchronous Release

The interaction of syntaxin 1A (Sx1A) with voltage-gated calcium channels (VGCC) is required for depolarization-evoked release. However, it is unclear how the signal is transferred from the channel to the exocytotic machinery and whether assembly of Sx1A and the calcium channel is conformationally l...

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Detalles Bibliográficos
Autores principales: Bachnoff, Niv, Cohen-Kutner, Moshe, Trus, Michael, Atlas, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621091/
https://www.ncbi.nlm.nih.gov/pubmed/23567899
http://dx.doi.org/10.1038/srep01620