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A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients

BACKGROUND: Studies on the association between MDM2 SNP309 (T > G) and gastric cancer have reported conflicting results. Thus, the aim of this study was to investigate whether MDM2 SNP309 is associated with susceptibility and prognosis of gastric carcinoma in Chinese patients. METHODS: Total of 5...

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Detalles Bibliográficos
Autores principales: Pan, Xiaolin, Li, Yuqin, Feng, Jin, Wang, Xiaoyong, Hao, Bo, Shi, Ruihua, Zhang, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621260/
https://www.ncbi.nlm.nih.gov/pubmed/23506213
http://dx.doi.org/10.1186/1471-2407-13-126