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Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

Current therapy for sickle cell disease (SCD) is limited to supportive treatment of complications, red blood cell transfusions, hydroxyurea, and stem cell transplantation. Difficulty in the translation of mechanistically based therapies may be the result of a reductionist approach focused on individ...

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Detalles Bibliográficos
Autor principal: Gee, Beatrice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621302/
https://www.ncbi.nlm.nih.gov/pubmed/23589705
http://dx.doi.org/10.1155/2013/694146