Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit

Correct execution of mitosis in eukaryotes relies on timely activation and inactivation of cyclin B-dependent kinase 1 (cdk1), the M-phase-promoting factor (MPF). Once activated, MPF is sustained until mitotic spindle assembly by phosphorylation-dependent feedback loops that prevent inhibitory phosp...

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Detalles Bibliográficos
Autores principales: Visconti, Roberta, Palazzo, Luca, Della Monica, Rosa, Grieco, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621406/
https://www.ncbi.nlm.nih.gov/pubmed/22692537
http://dx.doi.org/10.1038/ncomms1886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621406/
https://www.ncbi.nlm.nih.gov/pubmed/22692537
http://dx.doi.org/10.1038/ncomms1886

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