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Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit

Correct execution of mitosis in eukaryotes relies on timely activation and inactivation of cyclin B-dependent kinase 1 (cdk1), the M-phase-promoting factor (MPF). Once activated, MPF is sustained until mitotic spindle assembly by phosphorylation-dependent feedback loops that prevent inhibitory phosp...

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Detalles Bibliográficos
Autores principales:	Visconti, Roberta, Palazzo, Luca, Della Monica, Rosa, Grieco, Domenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621406/ https://www.ncbi.nlm.nih.gov/pubmed/22692537 http://dx.doi.org/10.1038/ncomms1886

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