The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice

Cachexia, or muscle-wasting syndrome, is one of the major causes of death in patients affected by diseases such as cancer, AIDS and sepsis. However, no effective anti-cachectic treatment is currently available. Here we show that a low dose of pateamine A, an inhibitor of translation initiation, prev...

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Detalles Bibliográficos
Autores principales: Di Marco, Sergio, Cammas, Anne, Lian, Xian Jin, Kovacs, Erzsebet Nagy, Ma, Jennifer F., Hall, Derek T., Mazroui, Rachid, Richardson, John, Pelletier, Jerry, Gallouzi, Imed Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621420/
https://www.ncbi.nlm.nih.gov/pubmed/22692539
http://dx.doi.org/10.1038/ncomms1899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621420/
https://www.ncbi.nlm.nih.gov/pubmed/22692539
http://dx.doi.org/10.1038/ncomms1899

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