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PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells
Signals that promote germ cell self-renewal by preventing premature meiotic entry are well understood. However, signals that control mitotic proliferation to promote meiotic differentiation have not been well characterized. In Caenorhabditis elegans, GLP-1 Notch signalling promotes the proliferative...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621483/ https://www.ncbi.nlm.nih.gov/pubmed/23487310 http://dx.doi.org/10.1242/dev.088013 |