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PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells

Signals that promote germ cell self-renewal by preventing premature meiotic entry are well understood. However, signals that control mitotic proliferation to promote meiotic differentiation have not been well characterized. In Caenorhabditis elegans, GLP-1 Notch signalling promotes the proliferative...

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Detalles Bibliográficos
Autores principales:	Vaid, Samir, Ariz, Mohd, Chaturbedi, Amaresh, Kumar, Ganga Anil, Subramaniam, Kuppuswamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Company of Biologists 2013
Materias:	Development and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621483/ https://www.ncbi.nlm.nih.gov/pubmed/23487310 http://dx.doi.org/10.1242/dev.088013

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