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A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins

The asymmetric localisation of core planar polarity proteins at apicolateral junctions is required to specify cell polarity in the plane of epithelia. This asymmetric distribution of the core proteins is proposed to require amplification of an initial asymmetry by feedback loops. In addition, genera...

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Detalles Bibliográficos
Autores principales: Strutt, Helen, Searle, Elizabeth, Thomas-MacArthur, Victoria, Brookfield, Rosalind, Strutt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621487/
https://www.ncbi.nlm.nih.gov/pubmed/23487316
http://dx.doi.org/10.1242/dev.089656