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A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins
The asymmetric localisation of core planar polarity proteins at apicolateral junctions is required to specify cell polarity in the plane of epithelia. This asymmetric distribution of the core proteins is proposed to require amplification of an initial asymmetry by feedback loops. In addition, genera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621487/ https://www.ncbi.nlm.nih.gov/pubmed/23487316 http://dx.doi.org/10.1242/dev.089656 |