[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice

BACKGROUND: Belinostat is a histone deacetylase inhibitor with anti-tumor effect in several pre-clinical tumor models and clinical trials. The aim of the study was to evaluate changes in cell proliferation and glucose uptake by use of 3’-deoxy-3’-[(18)F]fluorothymidine ([18F]FLT) and 2-deoxy-2-[(18)...

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Detalles Bibliográficos
Autores principales: Jensen, Mette Munk, Erichsen, Kamille Dumong, Johnbeck, Camilla Bardram, Björkling, Fredrik, Madsen, Jacob, Jensen, Peter Buhl, Sehested, Maxwell, Højgaard, Liselotte, Kjær, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621527/
https://www.ncbi.nlm.nih.gov/pubmed/23548101
http://dx.doi.org/10.1186/1471-2407-13-168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621527/
https://www.ncbi.nlm.nih.gov/pubmed/23548101
http://dx.doi.org/10.1186/1471-2407-13-168

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