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Transforming growth factor-β signaling in epithelial-mesenchymal transition and progression of cancer

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that induces growth arrest, tissue fibrosis, and epithelial-mesenchymal transition (EMT) through activation of Smad and non-Smad signaling pathways. EMT is the differentiation switch by which polarized epithelial cells differentiate...

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Detalles Bibliográficos
Autor principal: Miyazono, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621568/
https://www.ncbi.nlm.nih.gov/pubmed/19838011
http://dx.doi.org/10.2183/pjab.85.314