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Transforming growth factor-β signaling in epithelial-mesenchymal transition and progression of cancer
Transforming growth factor-β (TGF-β) is a multifunctional cytokine that induces growth arrest, tissue fibrosis, and epithelial-mesenchymal transition (EMT) through activation of Smad and non-Smad signaling pathways. EMT is the differentiation switch by which polarized epithelial cells differentiate...
Autor principal: | Miyazono, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621568/ https://www.ncbi.nlm.nih.gov/pubmed/19838011 http://dx.doi.org/10.2183/pjab.85.314 |
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