Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

Induced pluripotent stem cells (iPSC) have been generated from somatic cells by introducing reprogramming factors. Integration of foreign genes into the host genome is a technical hurdle for the clinical application. Here, we show that Sendai virus (SeV), an RNA virus and carries no risk of altering...

Descripción completa

Detalles Bibliográficos
Autores principales: Fusaki, Noemi, Ban, Hiroshi, Nishiyama, Akiyo, Saeki, Koichi, Hasegawa, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621571/
https://www.ncbi.nlm.nih.gov/pubmed/19838014
http://dx.doi.org/10.2183/pjab.85.348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621571/
https://www.ncbi.nlm.nih.gov/pubmed/19838014
http://dx.doi.org/10.2183/pjab.85.348

Ejemplares similares