Cargando…

Src Regulates the Activity of the ING1 Tumor Suppressor

The INhibitor of Growth 1 (ING1) is stoichiometric member of histone deacetylase (HDAC) complexes and functions as an epigenetic regulator and a type II tumor suppressor. It impacts cell growth, aging, apoptosis, and DNA repair, by affecting chromatin conformation and gene expression. Down regulatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Lisa, Thakur, Satbir, Leong-Quong, Rebecca YY., Suzuki, Keiko, Pang, Andy, Bjorge, Jeffrey D., Riabowol, Karl, Fujita, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621671/
https://www.ncbi.nlm.nih.gov/pubmed/23585863
http://dx.doi.org/10.1371/journal.pone.0060943