Cargando…

Src Regulates the Activity of the ING1 Tumor Suppressor

The INhibitor of Growth 1 (ING1) is stoichiometric member of histone deacetylase (HDAC) complexes and functions as an epigenetic regulator and a type II tumor suppressor. It impacts cell growth, aging, apoptosis, and DNA repair, by affecting chromatin conformation and gene expression. Down regulatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Lisa, Thakur, Satbir, Leong-Quong, Rebecca YY., Suzuki, Keiko, Pang, Andy, Bjorge, Jeffrey D., Riabowol, Karl, Fujita, Donald J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621671/ https://www.ncbi.nlm.nih.gov/pubmed/23585863 http://dx.doi.org/10.1371/journal.pone.0060943

Ejemplares similares

REAP: A two minute cell fractionation method
por: Suzuki, Keiko, et al.
Publicado: (2010)

Stromal ING1 expression induces a secretory phenotype and correlates with breast cancer patient survival
por: Thakur, Satbir, et al.
Publicado: (2015)

The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination
por: Thalappilly, Subhash, et al.
Publicado: (2011)

Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients
por: Bose, Pinaki, et al.
Publicado: (2014)

ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth
por: Thakur, Satbir, et al.
Publicado: (2012)

Reduced ING1 levels in breast cancer promotes metastasis
por: Thakur, Satbir, et al.
Publicado: (2014)

The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway
por: Rajarajacholan, Uma Karthika, et al.
Publicado: (2013)

Defining the minimal peptide sequence of the ING1b tumour suppressor capable of efficiently inducing apoptosis
por: Boyko, A, et al.
Publicado: (2015)

Biological Functions of the ING Proteins
por: Dantas, Arthur, et al.
Publicado: (2019)

ING1 induces apoptosis through direct effects at the mitochondria
por: Bose, P, et al.
Publicado: (2013)

ING1 induces apoptosis through direct effects at the mitochondria
por: Bose, P, et al.
Publicado: (2013)

The ING tumor suppressors in cellular senescence and chromatin
por: Ludwig, Susann, et al.
Publicado: (2011)

Aging with ING: a comparative study of different forms of stress induced premature senescence
por: Rajarajacholan, Uma Karthika, et al.
Publicado: (2015)

The roles of ING5 in cancer: A tumor suppressor
por: Zheng, Hua-chuan, et al.
Publicado: (2022)

Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line
por: Bjorge, Jeffrey D., et al.
Publicado: (2011)

ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization
por: Rajarajacholan, Uma Karthika, et al.
Publicado: (2017)

ING Proteins: Tumour Suppressors or Oncoproteins
por: Jacquet, Karine, et al.
Publicado: (2021)

Interspecies data mining to predict novel ING-protein interactions in human
por: Gordon, Paul MK, et al.
Publicado: (2008)

A minimal ING1b fragment that improves the efficacy of HDAC-based cancer cell killing
por: Boyko, A, et al.
Publicado: (2015)

ING Tumour Suppressors and ING Splice Variants as Coregulators of the Androgen Receptor Signalling in Prostate Cancer
por: Melekhova, Anna, et al.
Publicado: (2021)

ING3 promotes prostate cancer growth by activating the androgen receptor
por: Nabbi, Arash, et al.
Publicado: (2017)

ING1b-inducible microRNA203 inhibits cell proliferation
por: Chen, J, et al.
Publicado: (2013)

Loss of Ing3 Expression Results in Growth Retardation and Embryonic Death
por: Fink, Dieter, et al.
Publicado: (2019)

Identification of a Novel Function for the Chromatin Remodeling Protein ING2 in Muscle Differentiation
por: Eapen, Shawn A., et al.
Publicado: (2012)

Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors
por: Bartsch, Sophie, et al.
Publicado: (2021)

Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer
por: Byron, Sara A., et al.
Publicado: (2012)

Tumor suppressor ING4 inhibits estrogen receptor activity in breast cancer cells
por: Keenen, Madeline M, et al.
Publicado: (2016)

Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release
por: Bjorge, Jeffrey D., et al.
Publicado: (2017)

ING Genes Work as Tumor Suppressor Genes in the Carcinogenesis of Head and Neck Squamous Cell Carcinoma
por: Li, Xiaohan, et al.
Publicado: (2011)

Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein
por: McClurg, Urszula L, et al.
Publicado: (2018)

LincRNA-p21 acts as a mediator of ING1b-induced apoptosis
por: Tran, U M, et al.
Publicado: (2015)

The essential role of tumor suppressor gene ING4 in various human cancers and non-neoplastic disorders
por: Du, Yang, et al.
Publicado: (2019)

ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways
por: Wang, F, et al.
Publicado: (2018)

Q-ing tumor glutaminase therapy
por: Stine, Zachary E., et al.
Publicado: (2015)

Src-mediated phosphorylation converts FHL1 from tumor suppressor to tumor promoter
por: Wang, Xiang, et al.
Publicado: (2018)

Expression of the novel tumour suppressor p33(ING1) is independent of p53
por: Cheung, K-J J, et al.
Publicado: (2000)

Tumour suppressor ING1b maintains genomic stability upon replication stress
por: Wong, Ronald P. C., et al.
Publicado: (2011)

Archibald Inglis
Publicado: (1889)

Mallet-ing
Publicado: (1860)

Inge Borghuis
por: Kiers, Bart
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7qsbrj522ohccdtcj5f9153u1i