Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling

BACKGROUND: The few currently available drugs for treatment of African trypanosomiasis are outdated and show problems with toxicity and resistance. Hence, there is an urgent need for the discovery and development of new anti-trypanosomal agents. FINDINGS: In this study, the ionophorous antibiotic sa...

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Detalles Bibliográficos
Autores principales: Steverding, Dietmar, Sexton, Darren W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621689/
https://www.ncbi.nlm.nih.gov/pubmed/23517602
http://dx.doi.org/10.1186/1756-3305-6-78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621689/
https://www.ncbi.nlm.nih.gov/pubmed/23517602
http://dx.doi.org/10.1186/1756-3305-6-78

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