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Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling
BACKGROUND: The few currently available drugs for treatment of African trypanosomiasis are outdated and show problems with toxicity and resistance. Hence, there is an urgent need for the discovery and development of new anti-trypanosomal agents. FINDINGS: In this study, the ionophorous antibiotic sa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621689/ https://www.ncbi.nlm.nih.gov/pubmed/23517602 http://dx.doi.org/10.1186/1756-3305-6-78 |