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Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin

The Sleeping Beauty transposon system is used as a tool for insertional mutagenesis and oncogenesis. However, little is known about the exact histological phenotype of the tumors induced. Thus, we used immunohistochemical markers to enable histological identification of the type of tumor induced by...

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Detalles Bibliográficos
Autores principales: JUNG, SUNYOUNG, RO, SIMON WEONSANG, JUNG, GEUNYOUNG, JU, HYE-LIM, YU, EUN-SIL, SON, WOO-CHAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621733/
https://www.ncbi.nlm.nih.gov/pubmed/23380875
http://dx.doi.org/10.3892/or.2013.2264