Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter

BACKGROUND: Betaine is a methyl donor and has been considered as a lipotropic effect substance. But its mechanism remains unclear. Hepatic steatosis is associated with abnormal expression of genes involved in hepatic lipid metabolism. DNA methylation contributes to the disregulation of gene expressi...

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Detalles Bibliográficos
Autores principales: Wang, Lijun, Chen, Li, Tan, Yaozong, Wei, Jun, Chang, Ying, Jin, Tianru, Zhu, Huilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621752/
https://www.ncbi.nlm.nih.gov/pubmed/23497035
http://dx.doi.org/10.1186/1476-511X-12-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621752/
https://www.ncbi.nlm.nih.gov/pubmed/23497035
http://dx.doi.org/10.1186/1476-511X-12-34

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