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A New Approach to Establish a Cell Line with Reduced Risk of Endogenous Retroviruses
Endogenous retroviruses (ERVs) are integrated as DNA proviruses in the genomes of all mammalian species. Several ERVs are replication-competent and produced as fully infectious viruses from host cell. Thus, live-attenuated vaccines and biological substances have been prepared using the cell lines wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621756/ https://www.ncbi.nlm.nih.gov/pubmed/23585909 http://dx.doi.org/10.1371/journal.pone.0061530 |