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B-Cell Lymphopoiesis Is Regulated by Cathepsin L

Cathepsin L (CTSL) is a ubiquitously expressed lysosomal cysteine peptidase with diverse and highly specific functions. The involvement of CTSL in thymic CD4+ T-cell positive selection has been well documented. Using CTSL(nkt/nkt) mice that lack CTSL activity, we have previously demonstrated that th...

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Detalles Bibliográficos
Autores principales: Badano, Maria Noel, Camicia, Gabriela Lorena, Lombardi, Gabriela, Maglioco, Andrea, Cabrera, Gabriel, Costa, Hector, Meiss, Roberto Pablo, Piazzon, Isabel, Nepomnaschy, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621861/
https://www.ncbi.nlm.nih.gov/pubmed/23585893
http://dx.doi.org/10.1371/journal.pone.0061347