Focused Examination of the Intestinal Epithelium Reveals Transcriptional Signatures Consistent with Disturbances in Enterocyte Maturation and Differentiation during the Course of SIV Infection

The Gastrointestinal (GI) tract plays a pivotal role in AIDS pathogenesis as it is the primary site for viral transmission, replication and CD4(+) T cell destruction. Accordingly, GI disease (enteropathy) has become a well-known complication and a driver of AIDS progression. To better understand the...

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Detalles Bibliográficos
Autores principales: Mohan, Mahesh, Kaushal, Deepak, Aye, Pyone P., Alvarez, Xavier, Veazey, Ronald S., Lackner, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621888/
https://www.ncbi.nlm.nih.gov/pubmed/23593167
http://dx.doi.org/10.1371/journal.pone.0060122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621888/
https://www.ncbi.nlm.nih.gov/pubmed/23593167
http://dx.doi.org/10.1371/journal.pone.0060122

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