In Vivo Expansion of Co-Transplanted T Cells Impacts on Tumor Re-Initiating Activity of Human Acute Myeloid Leukemia in NSG Mice

Human cells from acute myeloid leukemia (AML) patients are frequently transplanted into immune-compromised mouse strains to provide an in vivo environment for studies on the biology of the disease. Since frequencies of leukemia re-initiating cells are low and a unique cell surface phenotype that inc...

Descripción completa

Detalles Bibliográficos
Autores principales: von Bonin, Malte, Wermke, Martin, Cosgun, Kadriye Nehir, Thiede, Christian, Bornhauser, Martin, Wagemaker, Gerard, Waskow, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621959/
https://www.ncbi.nlm.nih.gov/pubmed/23585844
http://dx.doi.org/10.1371/journal.pone.0060680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621959/
https://www.ncbi.nlm.nih.gov/pubmed/23585844
http://dx.doi.org/10.1371/journal.pone.0060680

Ejemplares similares