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DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review

In DNA methylation, methyl groups are covalently bound to CpG dinucleotides. However, the assumption that methyl groups are not lost during routine DNA extraction has not been empirically tested. To avoid nonbiological associations in DNA methylation studies, it is essential to account for potential...

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Detalles Bibliográficos
Autores principales: Soriano-Tárraga, Carolina, Jiménez-Conde, Jordi, Giralt-Steinhauer, Eva, Ois, Ángel, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Fernández-Cadenas, Israel, Montaner, Joan, Lucas, Gavin, Elosua, Roberto, Roquer, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621987/
https://www.ncbi.nlm.nih.gov/pubmed/23585847
http://dx.doi.org/10.1371/journal.pone.0060750