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Attenuation of cocaine and heroin seeking by μ-opioid receptor antagonism

RATIONALE: Evidence has implicated the endogenous opioids, in particular μ-opioid receptors, in emotional behavior and regulation of reward circuits, especially in the context of heroin addiction and hedonic responses to ingestive rewards. The μ-opioid receptor antagonist naltrexone (NTX) has been r...

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Detalles Bibliográficos
Autores principales: Giuliano, Chiara, Robbins, Trevor W., Wille, David R., Bullmore, Edward T., Everitt, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622002/
https://www.ncbi.nlm.nih.gov/pubmed/23299095
http://dx.doi.org/10.1007/s00213-012-2949-9