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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

Individual genetic variation affects gene expression in response to stimuli, often by influencing complex molecular circuits. Here we combine genomic and intermediate-scale transcriptional profiling with computational methods to identify variants that affect the responsiveness of genes to stimuli (r...

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Detalles Bibliográficos
Autores principales: Gat-Viks, Irit, Chevrier, Nicolas, Wilentzik, Roni, Eisenhaure, Thomas, Raychowdhury, Raktima, Steuerman, Yael, Shalek, Alex, Hacohen, Nir, Amit, Ido, Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622156/
https://www.ncbi.nlm.nih.gov/pubmed/23503680
http://dx.doi.org/10.1038/nbt.2519