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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli
Individual genetic variation affects gene expression in response to stimuli, often by influencing complex molecular circuits. Here we combine genomic and intermediate-scale transcriptional profiling with computational methods to identify variants that affect the responsiveness of genes to stimuli (r...
Autores principales: | Gat-Viks, Irit, Chevrier, Nicolas, Wilentzik, Roni, Eisenhaure, Thomas, Raychowdhury, Raktima, Steuerman, Yael, Shalek, Alex, Hacohen, Nir, Amit, Ido, Regev, Aviv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622156/ https://www.ncbi.nlm.nih.gov/pubmed/23503680 http://dx.doi.org/10.1038/nbt.2519 |
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