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The Role of E3 Ubiquitin Ligase Cbl Proteins in Interleukin-2-Induced Jurkat T-Cell Activation

Interleukin- (IL-) 2 is the major growth factor for T-cell activation and proliferation. IL-2 has multiple functions in the regulation of immunological processes. Although most studies focus on T-cell immunomodulation, T-cell activation by IL-2 is the foundation of priming the feedback loop. Here, w...

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Detalles Bibliográficos
Autores principales: Zhao, Ming-Fang, Qu, Xiu-Juan, Qu, Jing-Lei, Jiang, You-Hong, Zhang, Ye, Hou, Ke-Zuo, Deng, Hao, Liu, Yun-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622291/
https://www.ncbi.nlm.nih.gov/pubmed/23586039
http://dx.doi.org/10.1155/2013/430861