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Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice

The present study tested whether MG132 increases vascular nuclear factor E2-related factor-2 (Nrf2) expression and transcription to provide a therapeutic effect on diabetes-induced pathogenic changes in the aorta. To this end, three-month-old OVE26 diabetic and age-matched control mice were intraper...

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Detalles Bibliográficos
Autores principales: Miao, Xiao, Cui, Wenpeng, Sun, Weixia, Xin, Ying, Wang, Bo, Tan, Yi, Cai, Lu, Miao, Lining, Fu, Yaowen, Su, Guanfang, Wang, Yuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622385/
https://www.ncbi.nlm.nih.gov/pubmed/23589759
http://dx.doi.org/10.1155/2013/879516