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Effect of 7-Difluoromethyl-5, 4′-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE(−/−) mice induced by a cholesterol-rich diet

PURPOSE: 7-Difluoromethyl–5, 4′-dimethoxygenistein (DFMG), prepared by the difluoromethylation and alkylation of Genistein, is an active new chemical entity. Its anti-atherosclerosis effect was found in a series of studies in vitro. In this article, we explored and evaluated the anti-atherosclerosis...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Li, Lesai, You, Jiliang, Cao, Jianguo, Fu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622435/
https://www.ncbi.nlm.nih.gov/pubmed/23589679
http://dx.doi.org/10.2147/DDDT.S37512