Efficient production of chimeric mice from embryonic stem cells injected into 4- to 8-cell and blastocyst embryos

BACKGROUND: Production of chimeric mice is a useful tool for the elucidation of gene function. After successful isolation of embryonic stem (ES) cell lines, there are many methods for producing chimeras, including co-culture with the embryos, microinjection of the ES cells into pre-implantation embr...

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Detalles Bibliográficos
Autores principales: Hu, Minhua, Wei, Hengxi, Zhang, Jingfeng, Bai, Yinshan, Gao, Fenglei, Li, Li, Zhang, Shouquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622560/
https://www.ncbi.nlm.nih.gov/pubmed/23514327
http://dx.doi.org/10.1186/2049-1891-4-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622560/
https://www.ncbi.nlm.nih.gov/pubmed/23514327
http://dx.doi.org/10.1186/2049-1891-4-12

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