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Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons

BACKGROUND: Proinflammatory cytokine interleukin-1β (IL-1β) released from spinal microglia plays an important role in the maintenance of acute and chronic pain states. However, the cellular basis of this action remains poorly understood. Using whole-cell patch-clamp recordings, we examined the actio...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Jiang, Chang-Yu, Fujita, Tsugumi, Luo, Shi-Wen, Kumamoto, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622562/
https://www.ncbi.nlm.nih.gov/pubmed/23537341
http://dx.doi.org/10.1186/1744-8069-9-16