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Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons
BACKGROUND: Proinflammatory cytokine interleukin-1β (IL-1β) released from spinal microglia plays an important role in the maintenance of acute and chronic pain states. However, the cellular basis of this action remains poorly understood. Using whole-cell patch-clamp recordings, we examined the actio...
Autores principales: | Liu, Tao, Jiang, Chang-Yu, Fujita, Tsugumi, Luo, Shi-Wen, Kumamoto, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622562/ https://www.ncbi.nlm.nih.gov/pubmed/23537341 http://dx.doi.org/10.1186/1744-8069-9-16 |
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