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Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis

BACKGROUND: The insulin-like growth factor-1 (IGF-1) plays an important role in growth of prostate cancer (PCa) cells and facilitating the development and progression of PCa. This study aimed to evaluate the association of polymorphisms in three linkage disequilibrium (LD) blocks of the IGF-1 on the...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Norihiko, Narita, Shintaro, Inoue, Takamitsu, Saito, Mitsuru, Numakura, Kazuyuki, Huang, Mingguo, Hatakeyama, Shingo, Satoh, Shigeru, Saito, Seiichi, Ohyama, Chikara, Arai, Yoichi, Ogawa, Osamu, Habuchi, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622563/
https://www.ncbi.nlm.nih.gov/pubmed/23530598
http://dx.doi.org/10.1186/1471-2407-13-150