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Using graph models to find transcription factor modules: the hitting set problem and an exact algorithm

Systematically perturbing a cellular system and monitoring the effects of the perturbations on gene expression provide a powerful approach to study signal transduction in gene expression systems. A critical step of revealing a signal transduction pathway regulating gene expression is to identify tra...

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Detalles Bibliográficos
Autores principales: Lu, Songjian, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622577/
https://www.ncbi.nlm.nih.gov/pubmed/23324335
http://dx.doi.org/10.1186/1748-7188-8-2