A Quadruple Knockout of lasIR and rhlIR of Pseudomonas aeruginosa PAO1 That Retains Wild-Type Twitching Motility Has Equivalent Infectivity and Persistence to PAO1 in a Mouse Model of Lung Infection

It has been widely reported that quorum-sensing incapable strains of Pseudomonas aeruginosa are less virulent than wild type strains. However, quorum sensing mutants of P. aeruginosa have been shown to develop other spontaneous mutations under prolonged culture conditions, and one of the phenotypes...

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Detalles Bibliográficos
Autores principales: Lazenby, James J., Griffin, Phoebe E., Kyd, Jennelle, Whitchurch, Cynthia B., Cooley, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622596/
https://www.ncbi.nlm.nih.gov/pubmed/23593362
http://dx.doi.org/10.1371/journal.pone.0060973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622596/
https://www.ncbi.nlm.nih.gov/pubmed/23593362
http://dx.doi.org/10.1371/journal.pone.0060973

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