Fragments of the Bacterial Toxin Microcin B17 as Gyrase Poisons

Fluoroquinolones are very important drugs in the clinical antibacterial arsenal; their success is principally due to their mode of action: the stabilisation of a gyrase-DNA intermediate (the cleavage complex), which triggers a chain of events leading to cell death. Microcin B17 (MccB17) is a modifie...

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Detalles Bibliográficos
Autores principales: Collin, Frédéric, Thompson, Robert E., Jolliffe, Katrina A., Payne, Richard J., Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622597/
https://www.ncbi.nlm.nih.gov/pubmed/23593482
http://dx.doi.org/10.1371/journal.pone.0061459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622597/
https://www.ncbi.nlm.nih.gov/pubmed/23593482
http://dx.doi.org/10.1371/journal.pone.0061459

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