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A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues
BACKGROUND: RNA-seq, a next-generation sequencing based method for transcriptome analysis, is rapidly emerging as the method of choice for comprehensive transcript abundance estimation. The accuracy of RNA-seq can be highly impacted by the purity of samples. A prominent, outstanding problem in RNA-s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622628/ https://www.ncbi.nlm.nih.gov/pubmed/23735186 http://dx.doi.org/10.1186/1471-2105-14-S5-S11 |