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Bellerophon: a hybrid method for detecting interchromo-somal rearrangements at base pair resolution using next-generation sequencing data

BACKGROUND: Somatically-acquired translocations may serve as important markers for assessing the cause and nature of diseases like cancer. Algorithms to locate translocations may use next-generation sequencing (NGS) platform data. However, paired-end strategies do not accurately predict precise tran...

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Detalles Bibliográficos
Autores principales: Hayes, Matthew, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622635/
https://www.ncbi.nlm.nih.gov/pubmed/23734783
http://dx.doi.org/10.1186/1471-2105-14-S5-S6