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A novel min-cost flow method for estimating transcript expression with RNA-Seq

BACKGROUND: Through transcription and alternative splicing, a gene can be transcribed into different RNA sequences (isoforms), depending on the individual, on the tissue the cell is in, or in response to some stimuli. Recent RNA-Seq technology allows for new high-throughput ways for isoform identifi...

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Detalles Bibliográficos
Autores principales: Tomescu, Alexandru I, Kuosmanen, Anna, Rizzi, Romeo, Mäkinen, Veli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622638/
https://www.ncbi.nlm.nih.gov/pubmed/23734627
http://dx.doi.org/10.1186/1471-2105-14-S5-S15