Prioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles

BACKGROUND: Identification of gene-phenotype relationships is a fundamental challenge in human health clinic. Based on the observation that genes causing the same or similar phenotypes tend to correlate with each other in the protein-protein interaction network, a lot of network-based approaches wer...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Qin, Yufang, Liu, Taigang, Wang, Jun, Zheng, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622672/
https://www.ncbi.nlm.nih.gov/pubmed/23734762
http://dx.doi.org/10.1186/1471-2105-14-S5-S5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622672/
https://www.ncbi.nlm.nih.gov/pubmed/23734762
http://dx.doi.org/10.1186/1471-2105-14-S5-S5

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