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Prioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles
BACKGROUND: Identification of gene-phenotype relationships is a fundamental challenge in human health clinic. Based on the observation that genes causing the same or similar phenotypes tend to correlate with each other in the protein-protein interaction network, a lot of network-based approaches wer...
Autores principales: | Zhu, Jie, Qin, Yufang, Liu, Taigang, Wang, Jun, Zheng, Xiaoqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622672/ https://www.ncbi.nlm.nih.gov/pubmed/23734762 http://dx.doi.org/10.1186/1471-2105-14-S5-S5 |
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