Cargando…
NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents
AIMS/HYPOTHESIS: The activation of NADPH oxidase has been implicated in NEFA-induced beta cell dysfunction. However, the causal role of this activation in vivo remains unclear. Here, using rodents, we investigated whether pharmacological or genetic inhibition of NADPH oxidase could prevent NEFA-indu...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622749/ https://www.ncbi.nlm.nih.gov/pubmed/23429921 http://dx.doi.org/10.1007/s00125-013-2858-4 |