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Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine–phosphate–guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through wh...

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Detalles Bibliográficos
Autores principales: Dayeh, T. A., Olsson, A. H., Volkov, P., Almgren, P., Rönn, T., Ling, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622750/
https://www.ncbi.nlm.nih.gov/pubmed/23462794
http://dx.doi.org/10.1007/s00125-012-2815-7